Botanical Name Plant's Common Name Plant Family   

   MMP-AC0119 : Myrtenol

 
Compound Name  :

Myrtenol
 
  Compound Class  : Terpenoids  
  Synonyms  : Myrtenol; 2-PINEN-10-OL; (-)-Pin-2-ene-10-ol; alpha-Pinene-10-ol; Bicyclo[3.1.1]hept-2-ene-2-methanol, 6,6-dimethyl-;

 
  Compound Extracted from  : Myrtenol is extracted / reported from 1 Plant(s) of Melghat Flora as below


 
 
Molecular Formula  :

C10H16O
 
  Molecular Weight  : 152.23  
  InChi Key  :  
  IUPAC  :  
  InChi  :  
  Hydrogen Bond Donor count  : 1  
  Hydrogen Bond Acceptor count  : 1  
  Rotational Bond count  : 1  
  TPSA  : 20.2  
  LogP Value  :

1.6

 
 
Lipinski Rule of Five  :

Yes
 
  Ghose Filter  : No  
  Veber Filter  : Yes  
  Muegge Filter  :

No

 
 
PubChem CID  :

10582
 
  Drugbank ID  : -  
  Super Natural  : -  
  CTD  : C534317  
  HIT  : -  
  NCI-60 GI50 data  :

-

 
 
Reference(s)  :

https://www.ncbi.nlm.nih.gov/pubmed/18662739


 

Compound_ID Cell Lines Cancer Type IC50 Value EC50 Value ED50 Value GI50 Value References
MMP-AC0119 B16 Skin 300 µMol/L - - - 11741740

Compound_ID Target Gene_Name Gene_ID Cancer Cell_lines IC50 Value EC50 Value ED50 Value GI50 Value Remarks References
MMP-AC0119 RAP1A RAP1A, member of RAS oncogene family 5906 Leukemia K-562 - - - - Myrtenol was found to decrease the up-regulation of Rap1a. 12671036
MMP-AC0119 RHOA ras homolog family member A 387 Leukemia K-562 - - - - Myrtenol was found to decrease the up-regulation of RhoA induced by Lov. 12671036
MMP-AC0119 RHOB ras homolog family member B 388 Leukemia K-562 - - - - Myrtenol was found to decrease the up-regulation of RhoB induced by Lov. 12671036