Botanical Name Plant's Common Name Plant Family   

   MMP-AC0145 : Camphene

 
Compound Name  :

Camphene
 
  Compound Class  : Terpenoids  
  Synonyms  : CAMPHENE; 79-92-5; Comphene; 2,2-Dimethyl-3-methylenenorbornane; 3,3-Dimethyl-2-methylenenorbornane;

 
  Compound Extracted from  : Camphene is extracted / reported from 8 Plant(s) of Melghat Flora as below


 
 
Molecular Formula  :

C10H16
 
  Molecular Weight  : 136.23  
  InChi Key  :  
  IUPAC  :  
  InChi  :  
  Hydrogen Bond Donor count  : 0  
  Hydrogen Bond Acceptor count  : 0  
  Rotational Bond count  : 0  
  TPSA  : 0  
  LogP Value  :

3.3

 
 
Lipinski Rule of Five  :

Yes
 
  Ghose Filter  : No  
  Veber Filter  : Yes  
  Muegge Filter  :

No

 
 
PubChem CID  :

6616
 
  Drugbank ID  : -  
  Super Natural  : -  
  CTD  : C019286  
  HIT  : -  
  NCI-60 GI50 data  :

-

 
 
Reference(s)  :

https://www.ncbi.nlm.nih.gov/pubmed/23724298


 

Compound_ID Cell Lines Cancer Type IC50 Value EC50 Value ED50 Value GI50 Value References
MMP-AC0145 MCF-7 Breast - - - >250 µM 12802719
MMP-AC0145 B16 Skin 178 µMol/L - - - 11741740

Compound_ID Target Gene_Name Gene_ID Cancer Cell_lines IC50 Value EC50 Value ED50 Value GI50 Value Remarks References
MMP-AC0145 CASP3 caspase 3, apoptosis-related cysteine peptidase 836 Pancreatic Cancer MiaPaCa-2 - - - - Camphene stimulated caspase activity in a dose-dependent manner, from 1.75 to 4.5 fold. 20663038
MMP-AC0145 CASP7 caspase 7, apoptosis-related cysteine peptidase 840 Pancreatic Cancer MiaPaCa-2 - - - - Camphene stimulated caspase activity in a dose-dependent manner, from 1.75 to 4.5 fold. 20663038